[HTML][HTML] miR-98-5p alleviated epithelial-to-mesenchymal transition and renal fibrosis via targeting Hmga2 in diabetic nephropathy
Y Zhu, J Xu, W Liang, J Li, L Feng, PX Zheng… - International Journal of …, 2019 - hindawi.com
… Common variation of HMGA2 gene can greatly enhance nephropathy of type 2 diabetic patients
… In our research, it was displayed that HMGA2 was a target of miR-98-5p. We proved that …
… In our research, it was displayed that HMGA2 was a target of miR-98-5p. We proved that …
Long non-cording RNA XIST promoted cell proliferation and suppressed apoptosis by miR-423-5p/HMGA2 axis in diabetic nephropathy
H Chen, Y Guo, X Cheng - Molecular and Cellular Biochemistry, 2021 - Springer
… of DN included genetic susceptibility DN gene, increasing … Common genetic variants (single-nucleotide
polymorphisms, … roles in the progression of type 2 diabetes and non-alcoholic …
polymorphisms, … roles in the progression of type 2 diabetes and non-alcoholic …
The genetic map of diabetic nephropathy: evidence from a systematic review and meta-analysis of genetic association studies
… Although many genetic variants have been implicated in DN susceptibility, the results are …
The diabetes could be either Type I diabetes mellitus (T1DM) or Type II diabetes mellitus (…
The diabetes could be either Type I diabetes mellitus (T1DM) or Type II diabetes mellitus (…
[PDF][PDF] Serum circulating microRNA profiling for identification of potential markers of diabetic nephropathy in black African South Africans with type 2 diabetes mellitus
MSD Valentin - 2020 - wiredspace.wits.ac.za
… HMGA2 gene, that has been implicated in activation of the TGF-β1 signalling pathway. Thus,
increased … factors for T2DM have been linked to susceptibility to and development of insulin …
increased … factors for T2DM have been linked to susceptibility to and development of insulin …
Genetics of cardiovascular and renal complications in diabetes
RCW Ma - Journal of Diabetes Investigation, 2016 - Wiley Online Library
… for shared genetic susceptibility between type 2 diabetes, … in genetic factors for nephropathy
in type 1 and type 2 diabetes… for genetic variants for type 2 diabetes or type 2 diabetes-…
in type 1 and type 2 diabetes… for genetic variants for type 2 diabetes or type 2 diabetes-…
… ACTR2 aggravates the high glucose-induced cell dysfunction of human renal mesangial cells through mediating the miR-205-5p/HMGA2 axis in diabetic nephropathy
J Yun, J Ren, Y Liu, L Dai, L Song, X Ma, S Luo… - Diabetology & metabolic …, 2021 - Springer
… HMGA2 has been revealed to increase the risk of developing nephropathy in those patients
with type 2 diabetes … Also, our functional analysis suggested that HMGA2 could enhance the …
with type 2 diabetes … Also, our functional analysis suggested that HMGA2 could enhance the …
[HTML][HTML] A systems biology overview on human diabetic nephropathy: from genetic susceptibility to post-transcriptional and post-translational modifications
F Conserva, L Gesualdo, M Papale - Journal of diabetes research, 2016 - hindawi.com
… in this paper apply to DN secondary to type 2 diabetes (T2DN). … the common variants
responsible for the increased genetic … previously shown to increase susceptibility to oxidative …
responsible for the increased genetic … previously shown to increase susceptibility to oxidative …
Genetic predisposition in type 2 diabetes: a promising approach toward a personalized management of diabetes
MM Sirdah, NS Reading - Clinical Genetics, 2020 - Wiley Online Library
… The genetic factors are believed to be key predisposing determinants in individual susceptibility
to T2D. Therefore, identifying the predisposing genetic variants could be a crucial step in …
to T2D. Therefore, identifying the predisposing genetic variants could be a crucial step in …
[HTML][HTML] Genetic and epigenetic studies in diabetic kidney disease
HF Gu - Frontiers in genetics, 2019 - frontiersin.org
… –40% of diabetes patients. Epidemiological investigations and … highlighted an underlying
genetic susceptibility. Furthermore, … There are common variants such as rs3918242 (-1562C/T) …
genetic susceptibility. Furthermore, … There are common variants such as rs3918242 (-1562C/T) …
KCNQ1OT1/miR-18b/HMGA2 axis regulates high glucose-induced proliferation, oxidative stress, and extracellular matrix accumulation in mesangial cells
J Li, M Li, L Bai - Molecular and cellular biochemistry, 2021 - Springer
The dysregulated long noncoding RNAs (lncRNAs) are associated with the pathogenesis of
diabetic nephropathy (DN). LncRNA potassium voltage-gated channel subfamily Q member …
diabetic nephropathy (DN). LncRNA potassium voltage-gated channel subfamily Q member …